Mechanisms of Plasticity

long term potentiation in neuroplasticity process

Plasticity can occur through processes that take time, known as slow-onset changes, or through quicker process, known as fast-onset changes. Slow-onset changes are the anatomic changes of the neurons, including axonal growth, dendritic sprouting and neurogenesis--growing completely new structures, while fast onset changes are the activities that occur at the synaptic level. These kinds of fast-onset changes are known as synaptic modulation, which really means the ongoing process of strengthening or weakening of existing synapses. This process can be thought of much like the operation of your car, with the gas pedal representing excitation of synapses and the brake representing inhibition of synaptic responses. Thus, you really have two ways to make the brain go faster: strengthening synaptic connections through excitation (gas) and inhibition of other synaptic connections (brake). Persistent strengthening of synaptic connections through excitation (putting on the gas) develops long-term potentiation (LTP), or increasing the potential for that response to occur, while persistent weakening of other connections (putting on the brake) produces long-term depression (LTD) of a synaptic response.

<< previous page

next page: synaptogenisis >>


Contact Us

We will gladly answer all or your questions about rehabilitation at Centre for Neuro Skills.

email cns@neuroskills.com

phone 1.800.922.4994
or Request a Callback


brain injury store


free brain injury newsletter


why choose cns for brain injury rehabilitation


brain injury newsletter


brain injury store