Research Reports
Assessment
Reliability, Sensitivity, and Specificity of the VA Traumatic Brain Injury Screening Tool
1/9/12 ... The VATBIST appears to be a reliable and valid instrument.
The neurological wake-up test increases stress hormone levels in patients with severe traumatic brain injury
1/11/12 ... The neurological wake-up test induces a biochemical stress response in patients with severe traumatic brain injury.
Towards developing a guideline for vocational evaluation following traumatic brain injury
1/23/12 ... Vocation evaluation should include the assessment of: the meaning clients ascribe to work following a TBI and their post-injury goals; clients' self-perceptions of work competency, work readiness and anticipated challenges with return to work; and the available supports.
Reliability and validity of Questionnaire for Neurobehavioral Disability following traumatic brain injury
1/26/12 ... The present results indicate that this questionnaire has good reliability and validity, therefore it can be a significant indicator in TBI neurobehavioral disability study.
Validity of the Six-Minute Walk Test in individuals with traumatic brain injury
1/31/12 ... The 6MW provides a good estimate of peak aerobic capacity and some measures are more responsive to change than others in patients recovering from TBI.
Utility of routine follow-up head CT scanning after mild traumatic brain injury
2/13/12 ... A literature review of the efficacy of routine follow-up CT scans of the head after complicated mild traumatic brain injury (TBI).
Diagnostic confirmation of mild traumatic brain injury by diffusion tensor imaging: a case report
2/17/12 ... Minor traumatic brain injury is a common injury with variable clinical presentation. The system of diagnosis used in this case found a significant relationship between the clinical assessment and imaging results.
Microenvironment changes in mild traumatic brain injury
3/27/2012 ... It is crucial that a clinically useful evaluation and management procedure be instituted for MTBI that encompasses both molecular pathophysiology and functional outcome.
New high definition fiber tracking reveals damage caused by traumatic brain injury
3/5/2012 ... A powerful new imaging technique called High Definition Fiber Tracking (HDFT) will allow doctors to clearly see for the first time neural connections broken by traumatic brain injury (TBI).
The FOUR score predicts outcome in patients after traumatic brain injury
3/14/2012 ... The FOUR score is an accurate predictor of outcome in TBI patients. It has some advantages over GCS, such as all components of FOUR score but not GCS can be rated in intubated patients.
Predictive value of early radiological findings in inflicted traumatic brain injury
3/22/2012 ... Radiologic findings during the first month were significantly associated with the long-term outcome. Especially, basal ganglia lesions were associated with a poor outcome.
Identifying factors associated with perceived success in the transition from hospital to home after brain injury
4/10/2012 ... A combination of sentinel events and personal and environmental factors influences the perceptions of individuals and their families regarding the success of the transition from hospital to home.
Affect recognition, empathy and dysosmia following traumatic brain injury
4/16/2012 ... This study shows that olfactory deficits may be indicative of affect recognition impairments and reduced empathy.
Affect recognition, empathy and dysosmia following traumatic brain injury
4/16/2012 ... This study shows that olfactory deficits may be indicative of affect recognition impairments and reduced empathy.
A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury
4/26/2012 ... We believe that the enhanced sensitivity of newer and more advanced
neuroimaging techniques for identifying areas of brain damage in mTBI will be
important for documenting the biological basis of postconcussive symptoms, which
are likely associated with subtle brain alterations, alterations that have
heretofore gone undetected due to the lack of sensitivity of earlier neuroimaging
techniques.
Children
Cord Blood Stem Cells for Pediatric Traumatic Brain Injury
1/17/11 ... The University of Texas Health Science Center at Houston (UTHealth) has begun enrollment for the first Phase I safety study approved by the Food and Drug Administration to investigate the use of a child's own umbilical cord blood stem cells for traumatic brain injury in children.
Study finds headaches after traumatic brain injury highest in adolescents and girls
12/8/11 ... Headaches more frequent in youth 3 months after mild traumatic head injuries compared to those with arm injuries.
Spinal bleeding with brain injury may suggest abuse in young children
12/23/11 ... A new study found that spinal bleeding is found often in young children who are victims of abusive trauma.
Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms
1/4/11 ... Children with isolated severe injury mechanisms are at low risk of clinically important TBI, and many do not require emergent neuroimaging.
Intellectual outcome from preschool traumatic brain injury: A 5-year prospective, longitudinal study
1/5/11 ... This study has confirmed the high risk of persisting and global deficits associated with severe brain insult in early childhood.
Impact of posttraumatic stress disorder and injury severity on recovery in children with traumatic brain injury
1/13/12 ... children with TBI and PTSD did not experience as much psychosocial recovery as those without PTSD.
Social function in children and adolescents after traumatic brain injury: a systematic review
1/25/12 ... The weight of evidence confirmed an elevated risk of social impairment in the context of moderate and severe injury.
Intellectual, behavioral, and social outcomes of traumatic brain injury in early childhood
2/29/2012 ... Moderate/severe TBI at an early age appears to be associated with lowered intellectual function and possibly behavior problems. A child's environment influences cognitive and behavior function after TBI.
Early clinical indicators of developmental outcome in abusive head trauma
3/8/2012 ... This study demonstrates that clinical factors at the time of injury, such as early post-traumatic seizures and intubation requirement, are associated with poorer developmental outcome.
Predictors of cognitive function and recovery 10 years after traumatic brain injury in young children
3/9/2012 ... Results confirm a high risk of persisting deficits after severe TBI in early childhood.
Reliable change in postconcussive symptoms and its functional consequences among children with mild traumatic brain injury
3/16/2012 ... Many children with mild TBI show reliable increases in postconcussive symptoms that are associated with significant functional impairment in their daily lives.
Prevalence of traumatic brain injury in juvenile offenders: A meta-analysis
3/21/2012 ... Results suggest that the rate of TBIs within the juvenile offender population is significant and that there may be a relationship between TBIs and juvenile criminal behavior.
Parental distress, parenting practices, and child adaptive outcomes following traumatic brain injury
4/2/2012 ... Results suggest that parenting practices are an important area of focus for studies attempting to elucidate the relationship between parent and child functioning following TBI.
ADHD: An integration with pediatric traumatic brain injury
4/13/2012 ... ADHD following PTBI is even more common than the 30% rate the
current literature suggests.
Quality of life in children and adolescents post-TBI: A systematic review and meta-analysis
4/18/2012 ... Good outcomes are contingent
on milder injuries, proxy reporting and early assessment whereas poor outcomes reflect more severe injuries and later assessment (≤6 months vs. ≥ 1 year post-trauma, respectively).
Quality of life in children and adolescents post-TBI: A systematic review and meta-analysis
4/18/2012 ... Good outcomes are contingent on milder injuries, proxy reporting and early assessment whereas poor outcomes reflect more severe injuries and later assessment (≤6 months vs. ≥ 1 year post-trauma, respectively).
Weight gain after childhood traumatic brain injury: a matter of concern
5/7/2012 ... Weight gain of children during the first year after TBI was rapid and excessive. Male sex was a risk factor for excessive weight gain.
Premorbid child and family functioning as predictors of post-concussive symptoms in children with mild traumatic brain injuries
5/11/2012 ... Counter to expectations, post-concussive symptoms following mild TBI may actually be more apparent among children from higher-functioning families with greater resources.
Depression in children and adolescents in the first 6 months after traumatic brain injury
5/15/2012 ... Findings, which are similar to those reported after adult TBI, identify both similarities and differences in non-anxious and anxious depression following childhood TBI with respect to lesion laterality, genetic factors (in the form of family psychiatric history of anxiety disorder), age at injury, and more generalized affective dysregulation.
Dementia
Factor associated with an increased risk for subsequent development of Alzheimer's disease after TBI
5/3/2012 ... Induction of MCP-1 in response to TBI might be a potential predisposing factor that may increase the risk for development of Alzheimer's disease.
Neurophysiology
Electrical Brain Disturbances Linked to Worse Outcomes Following Neurotrauma
6/20/11 ... Electrical disturbances that spread through an injured brain like tsunamis have a direct link to poor recovery and can last far longer than previously realized, researchers at the University of Cincinnati Neuroscience Institute (UCNI) have found.
How Brain's Memory Center Repairs Damage from Head Injury
5/2/11 ... Researchers from UT Southwestern Medical Center have described for the first time how the brain's memory center repairs itself following severe trauma -- a process that may explain why it is harder to bounce back after multiple head injuries.
New understanding of brain chemistry could prevent brain damage after injury
6/6/11 ... A protective molecule has been identified in the brain which, if used artificially, may prevent brain damage from the likes of stroke, head injury and Alzheimer's.
Radar Shows Promise for Detecting Concussions in Athletes and Soldiers
5/23/11 ... Walking and thinking at the same time can be especially difficult for persons who've suffered concussions, and scientists hope to use that multitasking challenge -- measured by a simple radar system -- to quickly screen individuals who may have suffered brain injuries.
Study of how brain corrects perceptual errors has implications for brain injuries, robotics
3/28/11 ... New research provides the first evidence that sensory recalibration - the brain's automatic correcting of errors in our sensory or perceptual systems - can occur instantly.
Bioengineers Identify the Cellular Mechanisms of Traumatic Brain Injury
08/15/11 ... Bioengineers at Harvard have identified, for the very first time, the mechanism for diffuse axonal injury and explained why cerebral vasospasm is more common in blast-induced brain injuries than in brain injuries typically suffered by civilians.
Brain connectivity disrupted in patients with post-concussive syndrome
08/22/11 ... A new study has found that patients with mild traumatic brain injury (MTBI) exhibit abnormal functional connectivity in the thalamus, a centrally located relay station for transmitting information throughout the brain.
Brain tsunamis' are clue to helping victims of major head injuries
12/28/11 ... Treating 'brain tsunamis' or 'killer waves' could stop many victims of major head injury from suffering additional brain damage, a study published in Lancet Neurology has found.
Prognostic value of various intracranial pathologies in traumatic brain injury
1/3/12 ... Various intracranial pathologies in traumatic brain injury (TBI) can help to predict patient outcomes.
Challenges of identifying cognitive abilities in severely brain-injured patients
2/14/12 ... Only by employing complex machine-learning techniques to decipher repeated advanced brain scans were researchers at NewYork-Presbyterian/Weill Cornell able to provide evidence that a patient with a severe brain injury could, in her way, communicate accurately.
Concussive brain injury enhances fear learning and excitatory processes in the amygdala
3/30/2012 ... These results suggest that mild traumatic brain injury predisposes the brain toward heightened fear learning during stressful postinjury events and provides a potential molecular mechanism by which this occurs.
Brain-Injury data used to map intelligence in the brain
4/11/2012 ... Scientists report that they have mapped the physical architecture of intelligence in the brain.
New stem cell found in brain: Finding could be key to developing methods to heal and repair brain injury
4/24/2012 ... Researchers at Lund University in Sweden have discovered a new stem cell in the adult brain. These cells can proliferate and form several different cell types -- most importantly, they can form new brain cells.
Protection from traumatic brain injury in hormonally active women vs men of a similar age
5/9/2012 ... This study found no significant association between sex and mortality in either Victoria or Hong Kong and does not support the concept that females have better outcomes after traumatic brain injury.
Outcome
TBI 13 years on: factors associated with post-traumatic growth
1/18/12 ... Clinicians should be aware of PTG and how it is associated with factors such as "meaning" and "purpose" as well as demographic factors such as, social support, activity such as work, new and stable relationships, milder disability and a shift towards spiritual values.
Racial and ethnic disparities in employment outcomes for persons with traumatic brain injury
1/19/12 ... The odds of competitive employment were significantly greater for whites versus blacks and Hispanics.
Relationship between hyperglycemia and outcome in children with severe traumatic brain injury
1/20/12 ... In children with severe traumatic brain injury, hyperglycemia beyond the initial 48 hrs is associated with poor outcome.
Late presentations of minor head injury
2/3/12 ... Patients with minor head injury who present over 4 h post-insult exhibit a similar risk of intracranial pathology to those presenting within 4 h.
Effect of posttraumatic thyroid hormone levels on severity and mortality of patients with severe traumatic brain injury
2/15/12 ... The aim of this study is to evaluate the effect of thyroid hormones after traumatic brain injury in the severity and mortality and gain a clue in brain injury prognosis.
Memory and anatomical change in severe traumatic brain injury: 1 year vs. 8 year follow-up
2/24/12 ... The study indicated that cognitive recovery in severe TBI subjects had not been completed within 3-13 months post-injury, but also that the neural degeneration in severe TBI continues long after the head trauma.
Effects of a concussion may last longer than symptoms
3/6/2012 ... A recent study shows that physiological problems stemming from a concussion may continue to present in the patient even after standard symptoms subside.
Characteristics associated with satisfaction with life 1 year post traumatic brain injury in a population of Hispanic individuals
3/15/2012 ... Focusing rehabilitation efforts on improving cognition and vocational skills may improve SWLS in Hispanics 1 year post-TBI.
Impact of non-neurological complications in severe traumatic brain injury outcome
3/20/2012 ... Low initial GCS, worst first CT scan, intracranial hypertension and acute kidney injury determined hospital mortality in severe TBI patients.
Association of initial CT findings with quality-of-life outcomes for traumatic brain injury in children
3/26/2012 ... Associations exist between findings from the initial noncontrast head CT and quality of life score 12 months after injury in children with TBI.
Factors predicting functional and cognitive recovery following severe traumatic, anoxic, and cerebrovascular brain damage
3/27/2012 ... Patients with traumatic brain injury achieved greater functional and cognitive improvements than patients with cerebrovascular and anoxic ABI.
Long-term functional outcome of older adults after a traumatic brain injury
3/28/2012 ... The strongest and most consistent factors associated with independence in mobility and self-care were fewer comorbid conditions, no difficulty of access to home modification services and home support services, male gender, younger age at time of injury, and shorter acute care length of stay.
The association between traumatic brain injury and the subsequent risk of brain cancer
3/29/2012 ... Our findings suggest a positive correlation between TBI and the relatively short-term development of malignant neoplasms of the brain.
Glucose variability negatively impacts long-term functional outcome in patients with traumatic brain injury
4/20/2012 ... Glucose variability was significantly associated with poorer long-term functional outcome in patients with TBI as measured by the GOSE score.
Relationship of caregiver and family functioning to outcomes after postacute rehabilitation for traumatic brain injury
4/30/2012 ... Caregiver distress should be accounted for in studies investigating
the effectiveness of postacute rehabilitation after TBI.
Predictive biomarkers of recovery in traumatic brain injury
5/4/2012 ... In this review, we examine the various factors that must be taken into account in the search for a reliable non-invasive biomarkers in traumatic brain injury and their role in the diagnosis and outcome evaluation.
Prevention
Shielding Body Protects Brain From 'Shell Shocking' Blast Injuries
5/16/11 ... Stronger and tougher body armor to shield the chest, abdomen and back may be just what soldiers fighting in the Afghanistan and Iraq wars need to better protect their brains from mild injuries tied to so-called "shell shock," results of a Johns Hopkins study in mice suggest.
Probiotics reduce infections for traumatic brain injury patients in intensive care
12/19/11 ... New research shows that including probiotics with nutrients reduced the amount of time patients spent in intensive care.
Sports
Does Baseline Concussion Testing Really Reduce Risks to Athletes?
6/13/11 ... Baseline concussion tests given to hundreds of thousands of athletes might, paradoxically, increase risks in some cases, according to a Loyola University Health System researcher.
Study Takes Closer Look at Brain Abnormalities in Athletes with CTE
7/18/11 ... New Findings Provide Important Data for Refining Diagnosis.
Visual test effective in diagnosing concussions in collegiate athletes
09/06/11 ... A sideline visual test effectively detected concussions in collegiate athletes, according to a team of researchers from the Perelman School of Medicine at the University of Pennsylvania. Concussed athletes scored an average of 5.9 seconds slower (worse) than the best baseline scores in healthy controls on the timed test, in which athletes read a series of numbers on cards and are scored on time and accuracy.
Concussion Testing Should Not Overlook Physiology
12/21/11 ... Research finds impaired cerebrovascular reactivity among concussed athletes.
Routine Head Hits in School Sports May Cause Brain Injury
12/22/11 ... The brain scans of high school football and hockey players showed subtle injury -- even if they did not suffer a concussion -- after taking routine hits to the head during the normal course of play.
Study Shows Second Impact Syndrome Occurrences Increasing, New York Passes Concussion Management and Awareness Act
12/26/11 ... More and more sports athletes are suffering from Second Impact Syndrome (SIS). A study published in the Journal of Pediatrics draws attention to the potential dangers of interscholastic sports.
Second impact syndrome or cerebral swelling after sporting head injury
1/24/12 ... Second impact syndrome is believed to be the catastrophic consequence of repeated head injury in sport.
Statistics
Construction Industry Has Highest Number of Traumatic Brain Injuries in US Workplace
6/27/11 ... The construction industry had the highest number of TBIs and the agriculture, forestry, and fishing industry had the highest rates.
Traumatic brain injury in an aging population
1/12/12 ... Epidemiology of traumatic brain injury (TBI) is changing in several western countries, with an increasing proportion of elderly TBI patients admitted to ICU.
Traumatic brain injuries are likely more common than previously thought
2/16/12 ... Though researchers are becoming increasingly aware of the long-term effects of head injury, few studies have looked at the prevalence of traumatic brain injury (TBI) in all age groups, including males and females, taking into account both mild and serious events.
Symptoms
Risk Factors Predictive of Psychiatric Symptoms After Traumatic Brain Injury
7/25/11 ... A history of psychiatric illness such as depression or anxiety before a traumatic brain injury (TBI), together with other risk factors, are strongly predictive of post-TBI psychiatric disorders.
Survey Reveals Nearly 80 Percent of Respondents Suffer Added Burden of Neurologic Condition with Debilitating Social Impact
1/10/11 ... A survey released today by the Brain Injury Association of America (BIAA) indicates that approximately 80 percent of survey respondents experience symptoms of an additional neurologic condition called pseudobulbar affect (PBA).
Lack of Empathy Following Traumatic Brain Injury Associated With Reduced Responsiveness to Anger
8/1/11 ... A new study has recently revealed evidence of a relationship between physiological responses to anger and a reduction of emotional empathy post-injury.
Single Traumatic Brain Injury May Prompt Long-Term Neurodegeneration
8/8/11 ... Years after a single traumatic brain injury (TBI), survivors still show changes in their brains. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania suggest that Alzheimer's disease-like neurodegeneration may be initiated or accelerated following a single traumatic brain injury, even in young adults.
Traumatic Brain Injury Linked With Tenfold Increase in Stroke Risk
08/29/11 ... If you suffer traumatic brain injury, your risk of having a stroke within three months may increase tenfold, according to a new study.
Withdrawing Life Support for Traumatic Brain Injuries Needs Cautious Approach
09/12/11 ... Death following severe traumatic brain injury is associated with a highly variable incidence of withdrawal of life support at the end of life, finds a new study.
Low oxygen (hypoxia) is key factor affecting outcomes after traumatic brain injury
12/27/11 ... Study Has Important Implications for Patient Monitoring after Head Trauma.
Violent Crime, Epilepsy, and Traumatic Brain Injury
12/30/11 ... Commentary on research about the relationship between traumatic brain injury, epilepsy and violent crime.
Long-lasting TMS motor threshold elevation in mild traumatic brain injury
1/2/12 ... Results of a recent study show chronic motor threshold (MT) elevation in a sample of subjects with symptomatic or recovered MTBI.
Effect of osmotic agents on regional cerebral blood flow in traumatic brain injury
1/10/12 ... Osmotic agents, in addition to lowering ICP, improve CBF to hypoperfused brain regions in patients with intracranial hypertension after TBI.
Factors contributing to chronic fatigue after traumatic brain injury
1/17/12 ... Poor sleep, vitamin D deficiency, and anxiety were the most important factors associated with chronic fatigue after TBI.
Traumatic head injury in cluster headache: Cause or effect?
1/30/12 ... A better understanding of the association between head trauma and CH may provide important insights into both the pathophysiology of CH and the mechanisms by which traumatic head injury predisposes patients to developing headaches.
Development of posttraumatic stress disorder after mild traumatic brain injury
1/2/12 ... Results suggest that personality characteristics and attribution regarding the injury may impact the development of PTSD.
Influence of bodily injuries on symptom reporting following mild traumatic brain injury
2/6/12 ... In this study as the severity of bodily injuries increased, symptom burden decreased.
Depression following traumatic brain injury: Epidemiology, risk factors and management
2/7/12 ... It is important for clinicians to recognize major depression following traumatic brain injury (TBI) because of its association with poor global and psychosocial outcome, postconcussive symptoms and cognitive deficits.
Characteristics of acute posttraumatic headache following mild head injury
2/10/12 ... Study examines the prevalence and characteristics of acute posttraumatic headache (APTH) attributed to mild head injury within a prospective, observational study design.
Noise sensitivity in individuals following traumatic brain injury
2/23/12 ... Noise sensitivity is an important and under-researched symptom that can result from traumatic brain injury (TBI).
Traumatic brain injury impairs financial decision making skills
3/2/2012 ... People who experience a traumatic brain injury show a marked decline in the ability to make appropriate financial decisions in the immediate aftermath and a continued impairment on complex financial skills six months later.
Health care costs associated with traumatic brain injury and psychiatric illness in adults
3/12/2012 ... TBI and psychiatric illness were each associated with significant increases in health care costs; those with the combination of moderate-to-severe TBI and psychiatric illness had much higher costs than any other group.
An investigation of risk factors for postconcussional syndrome after mild traumatic brain injury
3/13/2012 ... The study provides good support for the proposed cognitive behavioural model. Patients' perceptions of their head injury and their behavioural responses play important roles in the development of PCS, indicating that cognitive and behavioural factors may be potential targets for early preventive interventions.
Predictors of postconcussive symptoms 3 months after mild traumatic brain injury
4/5/2012 ... Given the evident influence of both premorbid and concurrent psychiatric problems, especially anxiety, on postinjury symptoms, managing the anxiety response in vulnerable individuals with mTBI may be important to minimize ongoing sequelae.
Sleep Disturbances Among Soldiers with Combat Related Traumatic Brain Injury
4/6/2012 ... Sleep disruption is common following traumatic brain injuries and the majority developed a chronic sleep disorder.
Traumatic brain injury and disturbed sleep and wakefulness
4/17/2012 ... There is some evidence that reduced evening melatonin production due to traumatic brain damage may cause disruption of circadian regulation of sleep and wakefulness.
Prevalence of traumatic brain injury in intimate partner violence offenders compared to the general population: A meta-analysis
4/23/2012 ... TBI may be a risk factor for interpersonal violence, although comparatively few source studies, lack of standardized information about TBI severity, and the inability to investigate potential confounding variables necessarily limit this conclusion.
Changes in emotional empathy, affective responsivity, and behavior following severe traumatic brain injury
4/27/2012 ... The results represent the first to suggest that level of emotional empathy post traumatic brain injury may be associated with behavioral manifestations of disorders of drive and control.
The relations among cognitive impairment, coping style, and emotional adjustment following traumatic brain injury
5/8/2012 ... Greater impairments in cognition directly predicted higher levels of anxiety and depression following TBI.
Treatment
Cooling' Treatment Could Save Lives And Reduce Brain Damage
4/11/11 ... More people who suffer cardiac arrests could soon be offered a cooling treatment to reduce the risks of them dying or becoming severely brain damaged.
Protein and calories can help lessen effects of severe traumatic brain injury
5/9/11 ... Evidence from several studies of severely brain-injured patients shows that providing energy and protein to patients early reduces inflammation and improves their outcomes.
Religion benefits traumatic brain injury victims, Wayne State University research finds
7/5/11 ... Researchers find that if traumatic brain injury (TBI) victims feel close to a higher power, it can help them rehabilitate.
Researchers evaluate red wine compound for treating concussions
5/31/11 ... UT Southwestern Medical Center researchers are engaging the help of professional boxers and trainers to study whether a component in red wine and grapes could help reduce the short- and long-term effects of concussions.
Scientists Devise Way to Sort Brain Cells for Potential Transplants
7/11/11 ... University of Florida scientists have discovered a way to separate the neural wheat from the chaff during the process of generating brain cells for potential patient therapies.
Self-administered light therapy may improve cognitive function after traumatic brain injury
3/21/11 ... At-home, daily application of light therapy via light-emitting diodes (LEDs) placed on the forehead and scalp led to improvements in cognitive function and post-traumatic stress disorder in patients with a traumatic brain injury (TBI).
UCSF, UC Berkeley join forces to advance frontier of brain repair
4/4/11 ... Neuroscientists and engineers at UCSF and UC Berkeley have joined forces to help pioneer a new frontier of brain repair - the development of devices that would allow patients with such conditions as stroke, spinal cord injury, traumatic brain injury and Lou Gehrig's disease to control prosthetics through thoughts alone.
Human Skin Cells Converted Directly into Functional Neurons
09/19/11 ... Columbia University Medical Center researchers have for the first time directly converted human skin cells into functional forebrain neurons, without the need for stem cells of any kind.
Potential of simple injection on patients with head injury
09/26/11 ... New research has suggested that tranexamic acid has the potential to prevent people dying from head injuries.
Research shows Rx with hyperbaric oxygen improved TBI and PTSD in vets
12/01/11 ... Research has found that treatment with hyperbaric oxygen nearly three years after injury significantly improved function and quality of life for veterans with traumatic brain injury.
Effects of probiotics on clinical outcomes in severe traumatic brain-injured patients
12/29/11 ... Shorter ICU stays were observed among patients treated with probiotic therapy.
Prehospital fluid management in traumatic brain injury
1/6/12 ... The early management of patients who have sustained traumatic brain injury is aimed at preventing secondary brain injury through avoidance of cerebral hypoxia and hypoperfusion.
Physical exercise ameliorates deficits induced by traumatic brain injury
1/16/12 ... Physical exercise diminishes cerebral inflammation by elevating factors and agents involved in immunomodulatory function, and buttresses glial cell, cerebrovascular, and blood-brain barrier intactness. It provides unique non-pharmacologic intervention.
Families caring for US service members with traumatic brain injuries
1/27/12 ... Caregivers who provide assistance with either activities of daily living or instrumental activities of daily living may need additional resources to meet the long-term needs of their injured family member.
The adaption process to disability following acquired brain injury
2/1/12 ... Describes a new model of the adaptation process following acquired brain injury, based on the patient’s goals, the patient’s abilities and the emotional response to the changes and the possible discrepancy between goals and achievements.
Clinical pathways in head injury: improving the quality of care with early rehabilitation
2/8/12 ... A clinical pathway can improve the quality of care for all admissions with head injury and enhance the role for rehabilitation at an early stage.
Is management of acute traumatic brain injury effective?
2/9/12 ... To evaluate all the possible therapeutic measures concerning the acute management of traumatic brain injury (TBI) mentioned in Cochrane Systematic Reviews published in the Cochrane Database of Systematic Reviews (CDSR).
Critical care management of severe traumatic brain injury in adults
2/20/12 ... In this review, the critical care management of severe TBI will be discussed with focus on monitoring, avoidance and minimization of secondary brain insults, and optimization of cerebral oxygenation and CPP.
Effectiveness of cognitive behavior therapy for reducing anxiety following traumatic brain injury
2/21/12 ... study investigating the effectiveness of a 12-weekly anxiety treatment programme adapted for individuals with moderate-severe TBI, based on cognitive behaviour therapy (CBT) and Motivational Interviewing (MI).
New treatment for traumatic brain injury shows promise
2/22/12 ... A new drug is showing promise in shielding against the harmful effects of traumatic brain injury (TBI) in rats.
Adjustment to loss of the driving role following traumatic brain injury
2/28/2012 ... Driving cessation following TBI is associated with emotional, identity, transport and participation-related needs. An ongoing, individualised approach involving information, support and practical experiences may improve outcomes of driving cessation for people with TBI and their family members.
Systematic review of interventions for post-traumatic brain injury headache
3/1/2012 ... Although some guidelines are offered for PTHA management based on primary headache categories and treatments, no strong evidence from clinical trials is available to direct the treatment of PTHA.
Is aggressive treatment of severe traumatic brain injury cost effective?
3/7/2012 ... In every age group aggressive care resulted in better outcomes (more quality-adjusted years) than routine care, and routine care resulted in better outcomes than comfort care.
Physical exercise reduces deficits induced by traumatic brain injury
3/19/2012 ... Physical exercise diminishes cerebral inflammation by elevating factors and agents involved in immunomodulatory function, and buttresses glial cell, cerebrovascular, and blood–brain barrier intactness.
Skull resconstruction immediately following traumatic brain injury worsens brain damage
3/23/2012 ... Immediate skull reconstruction following trauma that penetrates or creates an indentation in the skull can aggravate brain damage inflicted by the initial injury.
Cognitive behavior therapy after acquired brain injury: Maintenance of therapeutic benefits at 6 months posttreatment
4/3/2012 ... The CBT adapted for ABI shows enduring benefits for mood and community integration.
Pharmacotherapy regimens among patients with posttraumatic stress disorder and mild traumatic brain injury
4/4/2012 ... The differences in drug therapy found in this study may indicate that patients with TBI and PTSD respond differently to treatment than patients with PTSD alone.
Anger self-management training for people with traumatic brain injury
4/9/2012 ... The treatment model represented by the ASMT appears worthy of further study in persons with TBI who have both problematic anger and cognitive impairment.
Acupuncture for treatment of insomnia in patients with traumatic brain injury: A pilot intervention study
4/12/2012 ... Acupuncture has a beneficial effect on perception of sleep or sleep quality and on cognition in our small sample of patients with TBI.
Use of hyperbaric oxygen in traumatic brain injury: Retrospective analysis of data of 20 patients treated at a tertiary care centre
4/19/2012 ... After the treatment, a significantly higher proportion of HBOT treated subjects showed a good response in cognitive functions, as measured by RLA.
Estrogen hormone reveals protective ability after traumatic brain injury
4/25/2012 ... Estrone, one of the three naturally occurring estrogen hormones in the body, has shown some promise in reducing inflammation and cell death in the brain.
Acupuncture for acute management and rehabilitation of traumatic brain injury
5/2/2012 ... The low methodological quality of the included studies does not allow us to make conclusive judgments on the efficacy and safety of acupuncture in either the acute treatment and/or rehabilitation of TBI. Its beneficial role for these indications remains uncertain.
Therapeutic hypothermia for severe traumatic brain injury: A critically appraised topic
5/10/2012 ... Current cumulative evidence does not support general use of therapeutic hypothermia for acute severe TBI. However, further investigation of the role of therapeutic hypothermia may be warranted for specific TBI subgroups.
Effectiveness of chin-down posture to prevent tracheal aspiration in dysphagia secondary to acquired brain injury. A videofluoroscopy study
5/14/2012 ... Only half the patients with acquired brain injury avoided aspiration during cervical flexion; 48% of silent aspirators continued to aspire during the maneuver. Several videofluoroscopic parameters were related to inefficiency of the maneuver.
An effective community-based mentoring program for return to work and school after brain injury
5/16/2012 ... Overall, findings suggest that mentoring can be beneficial toward achieving the goals of post-secondary education, employment and community independence for individuals with disabilities; specifically those with traumatic brain injury, spinal cord injury and other neurological disorders.
