Research Reports - Short-term persistence of oculomotor rehabilitative changes in mild traumatic brain injury
Brain Inj. 2015 Aug 21:1-5. [Epub ahead of print]
Thiagarajan P(1), Ciuffreda KJ(1).
PRIMARY OBJECTIVE: In our earlier published studies, oculomotor therapy (OMT) was
performed in 15 individuals with mild traumatic brain injury (mTBI) and over 90%
of the clinical oculomotor parameters abnormal at baseline significantly improved
immediately following the OMT. There was no placebo (P) effect on any of the
parameters. The purpose of the present pilot study was to assess the short-term
persistence of the previously obtained positive OMT findings.
RESEARCH DESIGN: Upon completion of the OMT, clinical oculomotor parameters were
re-assessed at 3-month and 6-month periods. No subsequent training was performed
during this 6-month period.
METHODS AND PROCEDURES: Clinical measures were repeated in eight of the 15
subjects who subsequently completed both the 3-month and 6-month follow-up
assessments. All measures were assessed using conventional clinical testing
MAIN OUTCOMES AND RESULTS: Eight of the 13 (62%) clinical oculomotor parameters
exhibited either persistence of, or delayed, improvement at the 3 and 6 month
CONCLUSIONS: Findings demonstrate both the presence and persistence of
oculomotor-based changes, suggestive of neural plasticity even in the adult,
compromised brain. Further studies are warranted to confirm and extend the
present pilot findings.