Research Reports - Alcohol intake and reduced mortality in patients with traumatic brain injury

Alcohol Clin Exp Res. 2016 Apr 21. doi: 10.1111/acer.13065. [Epub ahead of print]

Cho JS(1), Shin SD(2), Lee EJ(2), Song KJ(2), Noh H(3), Kim YJ(4), Lee SC(5),
Park JO(6), Kim SC(7), Hwang SS(8).

BACKGROUND: The purpose of our study was to determine whether alcohol intake
influences short-term mortality in patients with traumatic brain injury (TBI),
using a comprehensive trauma database.
METHODS: We collected data from 7 emergency departments (EDs) between June 1,
2008 and May 31, 2010, using the same data form. Cases were included if they met
the following criteria: (i) older than 15 and (ii) injuries including TBI.
Demographics and outcomes were compared between patients with and without alcohol
intake. We present the risk of mortality using hazard ratios and 95% confidence
intervals.
RESULTS: A total of 76,596 trauma patients visited the EDs during the study
period; 12,980 patients were older than 15 and had TBI. There were 4,009 (30.9%)
patients in the alcohol-intake group, of whom 3,306 (82.5%) patients were male,
1,450 (36.2%) patients were moved by ambulance, and 1,218 (30.4%) patients'
injuries were intentional. The most frequent injury mechanism was falling down
with alcohol intake and blunt injury without alcohol intake. Mortality rate was
1.0% with alcohol intake and 2.0% without alcohol intake. After adjusting for all
factors related to mortality, the hazard ratio of mortality was 0.72 in the
alcohol-intake group.
CONCLUSIONS: Mortality rate due to TBI in the alcohol-intake group appears to be
lower compared to that in the no-alcohol-intake group after adjusting for main
confounding variables. 

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