Research Reports - Sex-specific predictors of inpatient rehabilitation outcomes after traumatic brain injury

Arch Phys Med Rehabil. 2016 Jan 30. pii: S0003-9993(16)00046-0. doi:
10.1016/j.apmr.2016.01.011. [Epub ahead of print]

Chan V(1), Mollayeva T(2), Ottenbacher KJ(3), Colantonio A(2).

OBJECTIVE: To identify sex-specific predictors of inpatient rehabilitation
outcomes among patients with a traumatic brain injury (TBI) from a population
based perspective.
DESIGN: Retrospective cohort study SETTING: Ontario, Canada PARTICIPANTS:
Patients in inpatient rehabilitation for a TBI within one year of acute care
discharge between 2008/09 and 2011/12 (N=1,730, 70% male, 30% female).
INTERVENTIONS: None MAIN OUTCOME MEASURES: Inpatient rehabilitation length of
stay, total Functional Independence Measure (FIM™) score, and motor and cognitive
FIM™ ratings at discharge.
RESULTS: Sex, as a covariate in multivariable linear regression models, was not a
significant predictor of rehabilitation outcomes. While many of the predictors
examined were similar across males and females, sex-specific multivariable models
identified some predictors of rehabilitation outcome that are specific for males
and females; mechanism of injury (p<.0001) was a significant predictor of
functional outcome only among females while comorbidities (p<.0001) was a
significant predictor for males only.
CONCLUSIONS: Predictors of outcomes after inpatient rehabilitation differed by
sex, providing evidence for a sex-specific approach in planning and resource
allocation for inpatient rehabilitation services for patients with TBI. 

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