Research Reports - Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries
Alzheimers Dement (Amst). 2017 Mar 2;6:196-200. doi: 10.1016/j.dadm.2017.01.008.
eCollection 2017.
Li W(1), Risacher SL(2), McAllister TW(3), Saykin AJ(2); Alzheimer's Disease
Neuroimaging Initiative.
INTRODUCTION: The association between age at injury (AAI) and long-term cognitive
outcome of traumatic brain injuries (TBI) is debatable.
METHODS: Eligible participants with a history of TBI from Alzheimer's Disease
Neuroimaging Initiative were divided into a childhood TBI (cTBI) group (the
AAI ≤ 21 years old) and an adult TBI (aTBI) group (the AAI > 21 years old).
RESULTS: The cTBI group has a higher Everyday Cognition total score than the aTBI
group. All perceived cognitive functions are worse for the cTBI group than for
the aTBI group except memory. By contrast, the cTBI group has higher assessment
scores on either the Boston Naming Test or Rey Auditory Verbal Learning Test than
the aTBI group.
DISCUSSION: The AAI is associated with the long-term cognitive outcomes in older
adults with a history of TBI.
