Research Reports - The association between depression and traumatic brain injury in older adults

J Aging Health. 2017 May 1:898264317708072. doi: 10.1177/0898264317708072. [Epub
ahead of print]

McGuire C(1), Kristman VL(1)(2)(3)(4), Martin L(1), Bédard M(1)(4).

OBJECTIVE: Determine association between depression and traumatic brain injury
(TBI) in the older adult home care population of Ontario, Canada (2003-2013).
METHOD: A nested matched case control study was used, and data were retrieved for
service users 65 years or older who received home care between 2003 and 2013.
Incident TBI cases were matched to four controls by sex, age, and assessment
date. Odds ratios and multivariable conditional logistic regression were
RESULTS: 554,313 service users were included of which 5,215 (0.9%) had a TBI and
39,048 (7.0%) had depression. Fall history was an effect modifier. The
association between depression and TBI was 1.10 (95% confidence interval [CI] =
[0.93, 1.31]) for those without a history of falling, while for those with a
history of falling it was 1.24 (95% CI = [1.03, 1.48]) after adjusting for
education and Alzheimer's disease.
DISCUSSION: Depression is associated with sustaining a TBI in those with a
history of falling. 

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