Research Reports - Risk factors for new-onset depression after first-time traumatic brain injury

Psychosomatics. 2017 Jul 20. pii: S0033-3182(17)30161-5. doi:
10.1016/j.psym.2017.07.008. [Epub ahead of print]

Roy D(1), Koliatsos V(2), Vaishnavi S(3), Han D(4), Rao V(5).

BACKGROUND: Major depression after traumatic brain injury (TBI) has devastating
consequences as it increases the risk of suicide, impairs overall quality of
life, and affects interpersonal, occupational, and social functioning. Although
the literature has reported factors associated with depression after TBI, very
few studies have examined the prevalence and correlates focused on the
development of new-onset depression (NOD) after first-time TBI. Our study aimed
to identify TBI- and non-TBI-related factors associated with the development of
NOD in the first year after TBI.
METHODS: A total of 103 subjects with first-time TBI were seen within 12 months
postinjury and evaluated for the development of NOD at 3, 6, and 12 months.
RESULTS: Frontal lobe functioning, frontal lesions, and pre-TBI/early post-TBI
social impairment were not found to be predictors of development of NOD within
the first year after injury. Decreased post-TBI social functioning as perceived
by the subject at 3, 6, and 12 months was found to be associated with NOD at each
of these time points, respectively.
CONCLUSION: The study findings highlight the importance of psychotherapeutic
interventions to address the individuals' overall perception of their social
impairment in the early-TBI period. This may help decrease the progression of
major depression within the first year after injury.

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