Research Reports - Individual profiles of predictors and their relations to 10 years outcome after childhood traumatic brain injury

Brain Inj. 2013;27(7-8):831-8

Aaro Jonsson C, Catroppa C, Godfrey C, Smedler AC, Anderson V

Abstract Background: Outcome after childhood traumatic brain injury (CTBI) is
heterogeneous, with several predictors influencing long-term outcome. Method:
This exploratory study used person-oriented cluster analysis to investigate
individual profiles of medical, psychological and social predictors and their
relation to longitudinal development in a sample of 127 participants with mild,
moderate and severe CTBI. Outcome of cognitive, adaptive and academic function
was measured at 30 months and 10 years post-injury. Results: A nine-cluster
solution, explaining 67% of the variance in the sample, resulted in two clusters
with individuals with mostly mild injuries, five with mostly moderate injured
individuals and two clusters with severely injured individuals. Best outcome at
10 years post-injury had a cluster with individuals with moderate injuries, young
age at injury, average socioeconomic status (SES) and high pre-injury adaptive
function. Worst outcome had a small cluster with severely injured individuals,
young age at injury, average SES and average pre-injury adaptive function.
Conclusions: The findings suggest that pre-injury adaptive function is an
influential predictor of outcome following moderate CTBI. Age at injury in the
severe group appears to have increased influence over time, with younger age at
injury associated with reduced outcome at 10 years after severe CTBI.

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