Research Reports - Predictive factors for 1-year outcome of a cohort of patients with severe traumatic brain injury (TBI)

Brain Inj. 2013;27(9):1000-7

Jourdan C, Bosserelle V, Azerad S, Ghout I, Bayen E, Aegerter P, Weiss JJ, Mateo, J, Lescot T, Vigué B, Tazarourte K, Pradat-Diehl P, Azouvi P

Abstract Objectives: To assess outcome and predicting factors 1 year after a
severe traumatic brain injury (TBI). Methods: Multi-centre prospective inception
cohort study of patients aged 15 or older with a severe TBI in the Parisian area,
France. Data were collected prospectively starting the day of injury. One-year
evaluation included the relatives-rating of the Dysexecutive Questionnaire
(DEX-R), the Glasgow Outcome Scale-Extended (GOSE) and employment. Univariate and
multivariate tests were computed. Results: Among 257 survivors, 134 were included
(mean age 36 years, 84% men). Good recovery concerned 19%, moderate disability
43% and severe disability 38%. Among patients employed pre-injury, 42% were
working, 28% with no job change. DEX-R score was significantly associated with
length of education only. Among initial severity measures, only the IMPACT
prognostic score was significantly related to GOSE in univariate analyses, while
measures relating to early evolution were more significant predictors. In
multivariate analyses, independent predictors of GOSE were length of stay in
intensive care (LOS), age and education. Independent predictors of employment
were LOS and age. Conclusions: Age, education and injury severity are independent
predictors of global disability and return to work 1 year after a severe TBI.

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