Research Reports - Impact of depression and PTSD on functional outcome and quality of life of patients with mild traumatic brain injury

J Neurotrauma. 2014 Oct 16

Haagsma JA(1), Scholten AC, Andriessen TM, Vos PE, Van Beeck EF, Polinder S

The impact of disability following traumatic brain injury (TBI), assessed by
functional measurement scales for TBI or by health-related quality of life
(HRQL), may vary because of a number of factors, including presence of depression
or posttraumatic stress disorder (PTSD). The aim of this study was to assess
prevalence and impact of depression and PTSD on functional outcome and HRQL 6 and
12 months following mild TBI. We selected a sample of 1919 TBI patients who
attended the Emergency Department (ED) followed by either hospital admission or
discharge to the home environment. The sample received postal questionnaires 6
and 12 months after treatment at the ED. The questionnaires included items
regarding socio-demographics, the SF-36, the PQoL, the Beck Depression Inventory
(BDI) and the Impact of Event Scale (IES). Main findings: 797 (42%) TBI patients
completed the 6 months follow-up survey. Depression and PTSD prevalence rates at
both 6 and 12 month follow-up were 7% and 9% respectively. Living alone was an
independent predictor of depression and/or PTSD at 6 and 12 month follow-up.
Depression and PTSD were associated with a significantly decreased functional
outcome (measured with Glasgow Outcome Scale Extended; GOSE) and HRQoL (measured
with SF-36 and Perceived Quality of Life Scale; PQoL). We conclude that
depression and/or PTSD are relatively common in our sample of TBI patients and
that it is associated with a considerable decrease in functional outcome and

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