Research Reports - Psychiatric disorders in children and adolescents 24 months after mild traumatic brain injury

J Neuropsychiatry Clin Neurosci. 2015 Spring;27(2):112-20

Max JE(1), Friedman K, Wilde EA, Bigler ED, Hanten G, Schachar RJ, Saunders AE,
Dennis M, Ewing-Cobbs L, Chapman SB, Yang TT, Levin HS

This study aimed to better understand the occurrence of novel psychiatric
disorders (NPDs) in children with mild traumatic brain injury (mTBI) in relation
to preinjury variables, injury-related variables, and concurrent neurocognitive
outcome. Eighty-seven children aged 5-14 years who had experienced mTBI were
studied from consecutive hospital admissions with semistructured psychiatric
interviews soon after injury (baseline). Fifty-four children were reassessed 24
months postinjury. Standardized instruments were used to evaluate injury
severity, lesion characteristics, preinjury variables (lifetime psychiatric
disorder, family psychiatric history, family function, socioeconomic status,
psychosocial adversity, adaptive function, and academic function), and finally,
postinjury neurocognitive and adaptive function. At 24 months postinjury, NPDs
had occurred in 17 of 54 (31%) participants. NPD at 24 months was related to
frontal white matter lesions and was associated with estimated preinjury reading,
preinjury adaptive function, and concurrent deficits in reading, processing
speed, and adaptive function. These findings extend earlier reports that the
psychiatric morbidity after mTBI in children is more common than previously
thought, and moreover, it is linked to preinjury individual variables and injury
characteristics and is associated with postinjury adaptive and neurocognitive

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