Research Reports - Concussions, traumatic brain injury, and the innovative use of omega-3s

J Am Coll Nutr. 2016 Jul;35(5):469-75. doi: 10.1080/07315724.2016.1150796.

Lewis MD(1).

Traumatic brain injury (TBI), with its diverse heterogeneity and prolonged
secondary pathogenesis, remains a clinical challenge. Clinical studies thus far
have failed to identify an effective treatment strategy when a combination of
targets controlling aspects of neuroprotection, neuroinflammation, and
neuroregeneration is needed. Omega-3 fatty acids (n-3FA) offer the advantage of
this approach. Although further clinical trial research is needed, there is a
growing body of strong preclinical evidence and clinical experience that suggests
that benefits may be possible from aggressively adding substantial amounts of
n-3FA to optimize the nutritional foundation of TBI, concussion, and
postconcussion syndrome patients. Early and optimal doses of n-3FA, even in a
prophylactic setting, have the potential to improve outcomes from this
potentially devastating problem. With evidence of unsurpassed safety and
tolerability, n-3FA should be considered mainstream, conventional medicine, if
conventional medicine can overcome its inherent bias against nutritional,
nonpharmacologic therapies.

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